Beef Lasagna
This beef lasagna combines a deeply flavored meat sauce made from ground beef, garlic, and red wine with a creamy ricotta cheese layer, delivering authentic Italian-American comfort food.
This beef lasagna combines a deeply flavored meat sauce made from ground beef, garlic, and red wine with a creamy ricotta cheese layer, delivering authentic Italian-American comfort food.


Check what you already have. We'll leave it off your shopping list.
CookOS may earn a commission from Instacart orders.
Prices vary by store
*Service fees apply. Instacart® and the Instacart logo are registered trademarks of Maplebear Inc. d/b/a Instacart.
In a large pot or Dutch oven, heat olive oil over medium-high heat. Add the ground beef and season with garlic powder, onion powder, salt, and pepper. Cook, breaking up the meat, until browned.
Remove the cooked beef from the pot and set aside on a paper towel-lined plate to drain excess grease.
Add a bit more olive oil to the same pot. Add the diced onion and cook until softened, about 5-7 minutes.
Stir in 4 cloves of minced garlic and cook for another minute until fragrant.
Pour in the red wine to deglaze the pot, scraping up any browned bits from the bottom. Let it reduce for a minute.
Add the diced tomatoes and tomato sauce to the pot. Stir to combine.
Stir in about 1/2 cup of the chopped parsley, the dried oregano, and red pepper flakes.
Return the cooked ground beef to the pot and stir everything together. Let the sauce simmer while you prepare the other components.
Cook the lasagna noodles according to package directions. Drain and set aside.
In a medium bowl, prepare the ricotta filling. Combine the ricotta cheese, the remaining 2 cloves of minced garlic, the remaining 1/4 cup of chopped parsley, the egg, and about 1/2 cup of shredded mozzarella. Season with salt and pepper and mix well.
Preheat your oven to 375°F (190°C).
Assemble the lasagna in a 9x13 inch baking dish. Start with a thin layer of meat sauce on the bottom.
Layer with cooked noodles, followed by more meat sauce, dollops of the ricotta mixture, and a sprinkle of mozzarella cheese.
Repeat the layers until the dish is full, ending with a final layer of noodles, sauce, and a generous amount of the remaining mozzarella cheese on top.
Cover the baking dish tightly with aluminum foil.
Bake for 25 minutes. Then, remove the foil and bake for another 20-25 minutes, until the cheese is melted, bubbly, and golden brown.
Let the lasagna rest for at least 10 minutes before slicing and serving. Garnish with additional fresh parsley if desired.
Store covered in the refrigerator up to 4 days. Reheat covered at 350°F until warmed through, about 20 minutes. Freezes well up to 3 months when wrapped tightly.
Yes. Assemble the lasagna completely, cover with foil, and refrigerate up to 24 hours before baking. Bake from cold, adding 10-15 minutes to cooking time.
This recipe uses standard lasagna noodles that should be boiled according to package directions, drained, and layered while still pliable.
Bake until the cheese on top is golden brown and bubbling at the edges, usually 35-45 minutes at 375°F. Let it rest 10 minutes before cutting.
Freeze unbaked lasagna wrapped tightly in foil for up to 3 months. Thaw overnight in the refrigerator and bake as directed, adding extra time if needed.
An 80/20 ground beef blend provides enough fat for flavor while staying manageable; avoid very lean beef (90/10) as it can taste dry.