Sweet and Sour Pork Tenderloin

Name: Sweet and Sour Pork Tenderloin Sheet Pan Dinner
Prep time: 15 min
Cook time: 40 min
Total time: 55 min
Yield: 6 servings
Cuisine: American
Ingredients: 2.15 lb pork tenderloin; 1 large yellow onion, chopped; 1 red bell pepper, chopped; 1 green bell pepper, chopped; 1 head of broccoli, cut into florets; 2 cups pineapple, cubed; 3 tbsp olive oil, divided; salt, to taste; black pepper, to taste; garlic powder, to taste; 2 tbsp all-purpose seasoning blend; 3/4 cup sweet and sour sauce, divided; 2 green onions, sliced; Cooked rice, for serving

This sheet pan sweet and sour pork tenderloin combines tender roasted pork with caramelized vegetables and pineapple in a glossy sauce, delivering restaurant-quality flavor with minimal cleanup.

🌍American 🏷️Sheet pan dinner 🏷️Pork tenderloin 🏷️Sweet and sour pork 🏷️Pineapple Weeknight meal

🏷️

🏷️Easy recipe

-0:00

cookinginthemidwestonTikTok

Total

55 min

Servings

6

Difficulty

Easy

Est. Cost

$26–$43

Recipe Source

View original recipe

From TikTok · by cookinginthemidwest

-0:00

cookinginthemidwestonTikTok

Ingredients

2.15 lb pork tenderloin
1 large yellow onion, chopped
1 red bell pepper, chopped
1 green bell pepper, chopped
1 head of broccoli, cut into florets
2 cups pineapple, cubed
3 tbsp olive oil, divided
salt, to taste
black pepper, to taste
garlic powder, to taste
2 tbsp all-purpose seasoning blend
3/4 cup sweet and sour sauce, divided
2 green onions, slicedoptional
Cooked rice, for servingoptional

14 Ingredients

Delivery in as fast as one hour.^*

Powered by Instacart

Prices vary by store

^*Service fees apply. Instacart^® and the Instacart logo are registered trademarks of Maplebear Inc. d/b/a Instacart.

Instructions

1
Preheat your oven to 375°F (190°C).
2
On a large sheet pan, combine the chopped onion, bell peppers, broccoli florets, and cubed pineapple.
3
Drizzle the vegetables and pineapple with about 2 tablespoons of olive oil and season with salt, black pepper, and garlic powder. Toss everything together to coat evenly.
4
Pat the pork tenderloins dry. Drizzle with the remaining 1 tablespoon of olive oil and season generously on all sides with the all-purpose seasoning blend.
5
Place the seasoned pork tenderloins in the center of the sheet pan, nestled amongst the vegetables.
6
Bake in the preheated oven for 35 minutes.
7
After 35 minutes, carefully remove the pan from the oven and drizzle about half of the sweet and sour sauce over the pork tenderloins.
8
Return the pan to the oven and bake for an additional 5 minutes, or until the sauce has thickened slightly and the pork is cooked through.
9
Remove the pan from the oven and let the pork rest for 5-10 minutes before slicing.
10
Slice the pork tenderloin against the grain. Drizzle with the remaining sweet and sour sauce and garnish with sliced green onions.
11
Serve the sweet and sour pork and roasted vegetables over a bed of cooked rice.

Was this recipe helpful?

Tips & Notes

Pro tips

Pat the pork tenderloin dry and let it reach room temperature for 15-20 minutes before roasting for even cooking.
Cut vegetables into similar-sized pieces so they cook evenly with the pork; broccoli and peppers should be bite-sized.
Use a meat thermometer to check doneness at 145°F internal temperature—don't rely on timing alone as tenderloin size varies.
Toss vegetables with the pork halfway through roasting to ensure even caramelization and sauce coating.

Substitutions

Bell peppers → snap peas or sugar snap peas (reduces cooking time by 5 minutes)
Pineapple → mango or peaches (use same quantity; note slightly different sweetness level)
Broccoli → cauliflower florets or green beans (both roast in similar time)
Olive oil → avocado oil or vegetable oil (no flavor impact)

Storage & make-ahead

Store leftovers covered in an airtight container in the refrigerator for up to 3 days; reheat gently at 325°F until warmed through to preserve pork tenderness.