Mississippi Chicken and Rice Casserole

Name: Mississippi Chicken and Rice Casserole
Prep time: 10 min
Cook time: 1 h
Total time: 1 h 10 min
Yield: 4 servings
Cuisine: American
Ingredients: 1 cup long-grain white rice; 1 (10.5 oz) can cream of chicken soup, unsalted; 10.5 oz chicken broth; 1 (1 oz) packet au jus gravy mix, divided; 1 (1 oz) packet ranch seasoning mix, divided; 1.5 lbs boneless, skinless chicken breasts; 1/4 cup sliced pepperoncini peppers, plus more for garnish; 2 tbsp pepperoncini juice; 2 tbsp unsalted butter, cubed

Mississippi Chicken and Rice Casserole is a one-pan baked dish combining tender chicken breasts and long-grain rice in a creamy sauce flavored with ranch seasoning, au jus gravy mix, and tangy pepperoncini peppers. The dish delivers the bold, briny character of classic Mississippi pot roast in an accessible weeknight format.

🌍American 🏷️Mississippi chicken 🏷️Chicken and rice 🏷️Casserole 🏷️One-pan meal Weeknight dinner

🏷️

🏷️Comfort food

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TikTok

Total

1h 10m

Servings

4

Difficulty

Easy

Est. Cost

$19–$31

Recipe Source

View original recipe

From TikTok

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Ingredients

1 cup long-grain white rice
1 (10.5 oz) can cream of chicken soup, unsalted
10.5 oz chicken broth
1 (1 oz) packet au jus gravy mix, divided
1 (1 oz) packet ranch seasoning mix, divided
1.5 lbs boneless, skinless chicken breasts
1/4 cup sliced pepperoncini peppers, plus more for garnish
2 tbsp pepperoncini juice
2 tbsp unsalted butter, cubed

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Instructions

1
Preheat your oven to 350°F (175°C).
2
In a 9x13 inch baking dish, combine the long-grain rice, cream of chicken soup, and chicken broth.
3
Sprinkle in about half of the au jus gravy mix and half of the ranch seasoning mix. Stir everything together until well incorporated.
4
Nestle the chicken breasts on top of the rice mixture in a single layer.
5
Sprinkle the remaining au jus mix and ranch mix evenly over the chicken.
6
Arrange the sliced pepperoncini peppers over the chicken and drizzle with the pepperoncini juice.
7
Dot the top of the casserole with the cubed unsalted butter.
8
Cover the baking dish tightly with aluminum foil.
9
Bake for 1 hour, or until the chicken is cooked through and the rice is tender.
10
Remove from the oven, let rest for a few minutes, garnish with additional pepperoncini if desired, and serve.

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Tips & Notes

Pro tips

Cube the butter and distribute it across the casserole before baking to ensure even flavor distribution and prevent dry spots.
Stir the casserole halfway through baking to distribute the sauce evenly and prevent rice from sticking to the bottom.
Reserve additional pepperoncini peppers and their juice for garnish; the fresh brightness balances the creamy sauce.

Substitutions

cream of chicken soup → cream of mushroom soup (slightly earthier flavor, still creamy)
long-grain white rice → jasmine or basmati rice (similar cooking time and texture)
unsalted butter → salted butter (reduce salt from seasoning packets by ¼ teaspoon)

Storage & make-ahead

Store covered in the refrigerator for up to 4 days. Reheat covered at 325°F until warmed through, about 20 minutes, or microwave individual portions with a splash of broth.

Common Questions

Can I use chicken thighs instead of breasts?

Yes. Chicken thighs will stay moister during baking and add richer flavor. Increase baking time by 5–10 minutes and check internal temperature reaches 165°F.

Can I make this ahead of time?

Assemble the casserole (minus baking) up to 24 hours ahead, cover, and refrigerate. Add 5–10 minutes to bake time when cooking from cold.

What if I don't have pepperoncini peppers?

Substitute with diced banana peppers or pickled jalapeños for similar tangy heat, using 2 tbsp of their pickling liquid in place of pepperoncini juice.

How do I know when the chicken is done?

Insert a meat thermometer into the thickest part of the chicken; it should reach 165°F. Chicken will also be opaque and shred easily when fully cooked.

Can I double this recipe?

Yes. Double all ingredients and use a 9×13-inch baking dish. Baking time may increase by 10–15 minutes; check chicken temperature to confirm doneness.